Peptoid NPhe(4) in AGRP-Based c[Pro(1)-Arg(2)-Phe(3)-Phe(4)-Xxx(5)-Ala(6)-Phe(7)-DPro(8)] Scaffolds Maintain Mouse MC4R Antagonist Potency

Ericson, MD; Freeman, KT; Haskell-Luevano, C

Haskell-Luevano, C (corresponding author), Univ Minnesota, Dept Med Chem, Minneapolis, MN 55455 USA.; Haskell-Luevano, C (corresponding author), Univ Minnesota, Inst Translat Neurosci, Minneapolis, MN 55455 USA.

ACS MEDICINAL CHEMISTRY LETTERS, 2020; 11 (10): 1942

Abstract

The melanocortin receptors are involved in numerous physiological functions and are regulated by agonists derived from the proopiomelanocortin gene tr......

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