Rescue of Function of Mutant Luteinising Hormone Receptors with Deficiencies in Cell Surface Expression, Hormone Binding, and Hormone Signalling

Newton, CL; Anderson, RC; Kreuchwig, A; Krause, G; Katz, AA; Millar, RP

Newton, CL (corresponding author), Univ Pretoria, Dept Immunol, Fac Hlth Sci, Private Bag X323, ZA-0031 Pretoria, South Africa.

NEUROENDOCRINOLOGY, 2021; 111 (5): 451

Abstract

Introduction: G protein-coupled receptor (GPCR) mutations are implicated in many diseases. Most inactivating mutations cause receptor misfolding and p......

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