Roflumilast-Mediated Phosphodiesterase 4D Inhibition Reverses Diabetes-Associated Cardiac Dysfunction and Remodeling: Effects Beyond Glucose Lowering

Xu, R; Fu, J; Hu, Y; Yang, X; Tao, X; Chen, L; Huang, K; Fu, Q

Fu, Q (通讯作者)，Huazhong Univ Sci & Technol, Sch Basic Med, Dept Pharmacol, Tongji Med Coll, Wuhan, Peoples R China.;Fu, Q (通讯作者)，Key Lab Drug Target Res & Pharmacodynam Evaluat H, Wuhan, Peoples R China.

DIABETES, 2022; 71 (8): 1660

Abstract

Patients with type 2 diabetes have a substantial risk of developing cardiovascular disease. Phosphodiesterase 4 (PDE4) dysregulation is of pathophysio......

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