High-Throughput Screening Identifies Idasanutlin as a Resensitizing Drug for Venetoclax-Resistant Neuroblastoma Cells

Vernooij, L; Bate-Eya, LT; Alles, LK; Lee, JY; Koopmans, B; Jonus, HC; Schubert, NA; Schild, L; Lelieveld, D; Egan, DA; Kerstjens, M; Stam, RW; Koster, J; Goldsmith, KC; Molenaar, JJ; Dolman, MEM

Dolman, MEM (corresponding author), Princess Maxima Ctr Pediat Oncol, Heidelberglaan 25, NL-3584 CT Utrecht, Netherlands.

MOLECULAR CANCER THERAPEUTICS, 2021; 20 (6): 1161

Abstract

Neuroblastoma tumors frequently overexpress the antiapoptotic protein B-cell lymphoma/leukemia 2 (BCL-2). We previously showed that treating BCL-2-dep......

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