Using Multidimensional Separations to Distinguish Isomeric Amino Acid-Bile Acid Conjugates and Assess Their Presence and Perturbations in Model Systems

Stewart, AK; Foley, MH; Dougherty, MK; Mcgill, SK; Gulati, AS; Gentry, EC; Hagey, LR; Dorrestein, PC; Theriot, CM; Dodds, JN; Baker, ES

Dodds, JN; Baker, ES (通讯作者),North Carolina State Univ, Dept Chem, Raleigh, NC 27695 USA.;Theriot, CM (通讯作者),North Carolina State Univ, Coll Vet Med, Dept Pathobiol & Populat Hlth, Raleigh, NC 27607 USA.;Dorrestein, PC (通讯作者),Univ Calif San Diego, Skaggs Sch Pharm & Pharmaceut Sci, Dept Pharmacol, La Jolla, CA 92093 USA.;Dorrestein, PC (通讯作者),Univ Calif San Diego, Skaggs Sch Pharm & Pharmaceut Sci, Dept Pediat, La Jolla, CA 92093 USA.

ANALYTICAL CHEMISTRY, 2023; 95 (41): 15357

Abstract

Bile acids play key roles in nutrient uptake, inflammation, signaling, and microbiome composition. While previous bile acid analyses have primarily fo......

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