Pharmacokinetics and safety of glecaprevir and pibrentasvir in HCV-negative subjects with hepatic impairment

Kosloski, MP; Wang, HY; Pugatch, D; Mensa, FJ; Gane, E; Lawitz, E; Marbury, TC; Preston, RA; Kort, J; Liu, W

Liu, W (reprint author), AbbVie Inc, Clin Pharmacol & Pharmacometr, N Chicago, IL 60064 USA.

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2019; 75 (2): 217

Abstract

PurposeThis study characterized the effects of hepatic impairment on the pharmacokinetics and safety of glecaprevir and pibrentasvir, two direct-actin......

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