Antagonizing apolipoprotein J chaperone promotes proteasomal degradation of mTOR and relieves hepatic lipid deposition

Duan, SD; Qin, N; Pi, JY; Sun, P; Gao, YT; Liu, LM; Li, ZH; Li, Y; Shi, LY; Gao, Q; Qiu, Y; Tang, SQ; Wang, CH; Chen, TY; Wang, ST; Young, KC; Sun, HY

Sun, HY (通讯作者)，Natl Cheng Kung Univ, Coll Med, Dept Physiol, 1 Univ Rd, Tainan 70101, Taiwan.

HEPATOLOGY, 2023; 78 (4): 1182

Abstract

Background and Aims:Overnutrition-induced activation of mammalian target of rapamycin (mTOR) dysregulates intracellular lipid metabolism and contribut......

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