FATS regulates polyamine biosynthesis by promoting ODC degradation in an ER beta-dependent manner in non-small-cell lung cancer

Qiu, L; Hu, LF; Wang, HJ; Li, JL; Ruan, XH; Sun, BS; Zhi, JT; Zheng, XQ; Gu, L; Gao, M; Kong, PZ; Zhang, J

Zhang, J (corresponding author), Tianjin Med Univ Canc Inst & Hosp, Dept Breast Canc, Natl Clin Res Ctr Canc, Tianjins Clin Res Ctr Canc,Key Lab Breast Canc Pr, Tianjin 300060, Peoples R China.; Kong, PZ (corresponding author), Shanxi Med Univ, Dept Pathol, Taiyuan 030001, Shanxi, Peoples R China.; Kong, PZ (corresponding author), Shanxi Med Univ, Shanxi Key Lab Carcinogenesis & Translat Res Esop, Taiyuan 030001, Shanxi, Peoples R China.

CELL DEATH & DISEASE, 2020; 11 (10):

Abstract

Polyamine biosynthesis is an essential metabolic pathway for cell growth and differentiation in non-small-cell lung cancer (NSCLC). Fragile-site assoc......

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