Microglial NLRP3 Inflammasome Induces Excitatory Synaptic Loss Through IL-1β-Enriched Microvesicle Release: Implications for Sepsis-Associated Encephalopathy

Moraes, CA; Hottz, ED; Ornellas, DD; Adesse, D; De Azevedo, CT; D'Avila, JC; Zaverucha-Do-Valle, C; Maron-Gutierrez, T; Barbosa, HS; Bozza, PT; Bozza, FA

Bozza, FA (通讯作者),Fundacao Oswaldo Cruz, Evandro Chagas Natl Inst Infect Dis, FIOCRUZ, Rio De Janeiro, RJ, Brazil.;Bozza, FA (通讯作者),DOr Inst Res & Educ, Rio De Janeiro, RJ, Brazil.

MOLECULAR NEUROBIOLOGY, 2023; 60 (2): 481

Abstract

Acute cerebral dysfunction is a pathological state common in severe infections and a pivotal determinant of long-term cognitive outcomes. Current evid......

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