Junction resolving enzymes use multivalency to keep the Holliday junction dynamic

Zhou, RB; Yang, O; Declais, AC; Jin, H; Gwon, GH; Freeman, ADJ; Cho, Y; Lilley, DMJ; Ha, T

Zhou, RB; Ha, T (reprint author), Univ Illinois, Dept Phys, Champaign, IL 61820 USA.; Zhou, RB; Ha, T (reprint author), Univ Illinois, Ctr Phys Living Cells, Champaign, IL 61820 USA.; Zhou, RB (reprint author), Harvard Univ, Dept Chem & Chem Biol, Cambrid

NATURE CHEMICAL BIOLOGY, 2019; 15 (3): 269

Abstract

Holliday junction (HJ) resolution by resolving enzymes is essential for chromosome segregation and recombination-mediated DNA repair. HJs undergo two ......

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