Differences in Tumor Microenvironment Dictate T Helper Lineage Polarization and Response to Immune Checkpoint Therapy

Jiao, SP; Subudhi, SK; Aparicio, A; Ge, ZQ; Guan, BX; Miura, Y; Sharma, P

Sharma, P (reprint author), Univ Texas MD Anderson Canc Ctr, Dept Genitourinary Med Oncol, Houston, TX 77030 USA.; Sharma, P (reprint author), Univ Texas MD Anderson Canc Ctr, Dept Immunol, Houston, TX 77030 USA.; Sharma, P (reprint author), Univ Texas MD

CELL, 2019; 179 (5): 1177

Abstract

Immune checkpoint therapy (ICT) shows encouraging results in a subset of patients with metastatic castration-resistant prostate cancer (mCRPC) but sti......

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