Bardoxolone ameliorates TGF-beta 1-associated renal fibrosis through Nrf2/Smad7 elevation

Song, MK; Lee, JH; Ryoo, IG; Lee, SH; Ku, SK; Kwak, MK

Kwak, MK (reprint author), Catholic Univ Korea, Coll Pharm, 43 Jibong Ro, Bucheon 14662, Gyeonggi Do, South Korea.

FREE RADICAL BIOLOGY AND MEDICINE, 2019; 138 (): 33

Abstract

Transforming growth factor-beta (TGF-beta) is a potent pathogenic factor of renal injury through the upregulation of extracellular matrix (ECM) expres......

Full Text Link