The BDNF-TrkB signaling pathway in the rostral anterior cingulate cortex is involved in the development of pain aversion in rats with bone cancer via NR2B and ERK-CREB signaling

Li, JJ; Wang, X; Wang, H; Wang, RW; Guo, YJ; Xu, LC; Zhang, GF; Wu, JN; Wang, GM

Wang, GM (通讯作者),Shandong Univ, Dept Anesthesiol, Shandong Provincal Hosp, 324 Jingwu Rd, Jinan 250021, Peoples R China.

BRAIN RESEARCH BULLETIN, 2022; 185 (): 18

Abstract

Patients with bone cancer pain (BCP) are more prone to aversion. which not only causes mental distress but also aggravates BCP. However, the mechanism......

Full Text Link