Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma

Algazi, AP; Twitty, CG; Tsai, KK; Le, M; Pierce, R; Browning, E; Hermiz, R; Canton, DA; Bannavong, D; Oglesby, A; Francisco, M; Fong, L; Pittet, MJ; Arlauckas, SP; Garris, C; Levine, LP; Bifulco, C; Ballesteros-Merino, C; Bhatia, S; Gargosky, S; Andtbacka, RHI; Fox, BA; Rosenblum, MD; Daud, AI

Daud, AI (corresponding author), Univ Calif San Francisco, 1600 Divisadero St,Rm A741, San Francisco, CA 94113 USA.

CLINICAL CANCER RESEARCH, 2020; 26 (12): 2827

Abstract

Purpose: Tumors with low frequencies of checkpoint positive tumor-infiltrating lymphocytes (cpTIL) have a low likelihood of response to PD-1 blockade.......

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