Pulmonary toxicity is a common phenomenon of toxic pyrrolizidine alkaloids

Song, ZJ; He, YS; Ma, J; Fu, PP; Lin, G

Lin, G (corresponding author), Chinese Univ Hong Kong, Fac Med, Sch Biomed Sci, Hong Kong, Peoples R China.

JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS, 2020; 38 (2): 124

Abstract

The hepatotoxic pyrrolizidine alkaloids (PAs) are metabolically activated in the liver to form reactive dehydro-PAs, which generate pyrrole-protein ad......

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