Pleiotropic Effects of PPARD Accelerate Colorectal Tumorigenesis, Progression, and Invasion

Liu, Y; Deguchi, Y; Tian, R; Wei, DY; Wu, L; Chen, WD; Xu, WG; Xu, M; Liu, FY; Gao, S; Jaoude, JC; Chrieki, SP; Moussalli, MJ; Gagea, M; Morris, J; Broaddus, RR; Zuo, XS; Shureiqi, I

Zuo, XS; Shureiqi, I (reprint author), Univ Texas MD Anderson Canc Ctr, 1515 Holcombe Blvd, Houston, TX 77030 USA.

CANCER RESEARCH, 2019; 79 (5): 954

Abstract

APC mutations activate aberrant beta-catenin signaling to drive initiation of colorectal cancer; however, colorectal cancer progression requires addit......

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