LysoPCs induce Hck- and PKC delta-mediated activation of PKC gamma causing p47(phox) phosphorylation and membrane translocation in neutrophils

Kelher, MR; McLaughlin, NJD; Banerjee, A; Elzi, DJ; Gamboni, F; Khan, SY; Meng, XZ; Mitra, S; Silliman, CC

Silliman, CC (reprint author), Bonfils Blood Ctr, Res Lab, 717 Yosemite St, Denver, CO 80230 USA.

JOURNAL OF LEUKOCYTE BIOLOGY, 2017; 101 (1): 261

Abstract

Lysophosphatidylcholines (lysoPCs) are effective polymorphonuclear neutrophil (PMN) priming agents implicated in transfusion-related acute lung injury......

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