Long-read sequencing on the SMRT platform enables efficient haplotype linkage analysis in preimplantation genetic testing for beta-thalassemia

Wu, HT; Chen, DJ; Zhao, Q; Shen, XT; Liao, YB; Li, P; Chiu, PCN; Zhou, CQ

Zhou, CQ (通讯作者)，Sun Yat Sen Univ, Reprod Med Ctr, Affiliated Hosp 1, Guangzhou, Guangdong, Peoples R China.;Chiu, PCN (通讯作者)，Univ Hong Kong, Queen Mary Hosp, Dept Obstet & Gynaecol, Pokfulam, Hong Kong, Peoples R China.;Chiu, PCN (通讯作者)，Univ Hong Kong, Shenzhen Hosp, Shenzhen Key Lab Fertil Regulat, Dept Obstet & Gynecol, Shenzhen, Peoples R China.

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS, 2022; 39 (3): 739

Abstract

Purpose This study aimed to evaluate the value of long-read sequencing for preimplantation haplotype linkage analysis. Methods The genetic material of......

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