Selenium-GPX4 axis protects follicular helper T cells from ferroptosis

Yao, Y; Chen, Z; Zhang, H; Chen, CL; Zeng, M; Yunis, J; Wei, YB; Wan, YN; Wang, NA; Zhou, MZ; Qiu, C; Zeng, QX; Ong, HS; Wang, H; Makota, FV; Yang, Y; Yang, ZH; Wang, N; Deng, J; Shen, C; Xia, Y; Yuan, L; Lian, ZQ; Deng, YK; Guo, CL; Huang, AO; Zhou, PC; Shi, HB; Zhang, WT; Yi, HL; Li, DM; Xia, M; Fu, J; Wu, N; de Haan, JB; Shen, N; Zhang, WH; Liu, Z; Yu, D

Liu, Z (corresponding author), Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Otolaryngol Head & Neck Surg, Wuhan, Peoples R China.; Yu, D (corresponding author), Australian Natl Univ, John Curtin Sch Med Res, Dept Immunol & Infect Dis, Canberra, ACT, Australia.; Yu, D (corresponding author), Qilu Univ Technol, Shandong Acad Sci, Lab Immunol Environm & Hlth, Shandong Anal & Test Ctr, Jinan, Peoples R China.; Yu, D (corresponding author), Hubei Minzu Univ, Minda Hosp, Hubei Prov

NATURE IMMUNOLOGY, 2021; 22 (9): 1127

Abstract

Follicular helper T (T-FH) cells are a specialized subset of CD4(+) T cells that essentially support germinal center responses where high-affinity and......

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