Bronchial thermoplasty decreases airway remodelling by blocking epithelium-derived heat shock protein-60 secretion and protein arginine methyltransferase-1 in fibroblasts

Sun, QZ; Fang, L; Roth, M; Tang, XM; Papakonstantinou, E; Zhai, WQ; Louis, R; Heinen, V; Schleich, FN; Lu, SM; Savic, S; Tamm, M; Stolz, D

Roth, M (reprint author), Univ Hosp Basel, Petersgraben 4, CH-4031 Basel, Switzerland.; Roth, M (reprint author), Univ Hosp Basel, Dept Biomed, Pulm Cell Res, Petersgraben 4, CH-4031 Basel, Switzerland.

EUROPEAN RESPIRATORY JOURNAL, 2019; 54 (6):

Abstract

Bronchial thermoplasty (BT) is to date the only therapy that provides a lasting reduction in airway wall remodelling. However, the mechanism of action......

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