Histamine-induced biphasic activation of RhoA allows for persistent RhoA signaling

Zhang, JSZ; Nguyen, AH; Miyamoto, S; Brown, JH; McCulloch, AD; Zhang, J

Zhang, J (corresponding author), Univ Calif San Diego, Dept Bioengn, La Jolla, CA 92093 USA.; Zhang, J (corresponding author), Univ Calif San Diego, Dept Pharmacol, La Jolla, CA 92093 USA.

PLOS BIOLOGY, 2020; 18 (9):

Abstract

The small GTPase RhoA is a central signaling enzyme that is involved in various cellular processes such as cytoskeletal dynamics, transcription, and c......

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