Development of a Rapid Adeno-Associated Virus (AAV) Identity Testing Platform through Comprehensive Intact Mass Analysis of Full-Length AAV Capsid Proteins

Smith, J; Guapo, F; Strasser, L; Millán-Martín, S; Milian, SG; Snyder, RO; Bones, J

Bones, J (通讯作者)，Natl Inst Bioproc Res & Training, Characterisat & Comparabil Lab, Dublin A94 X099, Ireland.;Bones, J (通讯作者)，Univ Coll Dublin, Sch Chem & Bioproc Engn, Dublin D04 V1W8, Ireland.

JOURNAL OF PROTEOME RESEARCH, 2023; 23 (1): 161

Abstract

Adeno-associated viruses (AAVs) are commonly used as vectors for the delivery of gene therapy targets. Characterization of AAV capsid proteins (VPs) a......

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