A Combinatorial Strategy for Targeting BRAF(V600E)-Mutant Cancers with BRAF(V600E) Inhibitor (PLX4720) and Tyrosine Kinase Inhibitor (Ponatinib)

Ghosh, C; Kumar, S; Kushchayeva, Y; Gaskins, K; Boufraqech, M; Wei, D; Gara, SK; Zhang, LS; Zhang, YQ; Shen, M; Mukherjee, S; Kebebew, E

CLINICAL CANCER RESEARCH, 2020; 26 (8): 2022

Abstract

Purpose: Most aggressive thyroid cancers are commonly associated with a BRAF(V600E) mutation. Preclinical and clinical data in BRAF(V600E) cancers sug......

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