An overview of PROTACs: a promising drug discovery paradigm

Liu, Z; Hu, MX; Yang, Y; Du, CH; Zhou, HX; Liu, CYL; Chen, YW; Fan, L; Ma, HQ; Gong, YL; Xie, YM

Xie, YM (通讯作者),Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Peoples R China.;Xie, YM (通讯作者),Sichuan Univ, West China Hosp, Dept Lab Med, Canc Ctr, Chengdu 610041, Peoples R China.;Gong, YL (通讯作者),Sichuan Univ, West China Hosp, Dept OfThorac Oncol, Chengdu 610041, Peoples R China.

MOLECULAR BIOMEDICINE, 2022; 3 (1):

Abstract

Proteolysis targeting chimeras (PROTACs) technology has emerged as a novel therapeutic paradigm in recent years. PROTACs are heterobifunctional molecu......

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