Synthesis and preliminary structure-activity relationship study of 3-methylquinazolinone derivatives as EGFR inhibitors with enhanced antiproliferative activities against tumour cells

Zhang, Y; Wang, Q; Li, LL; Le, Y; Liu, L; Yang, J; Li, YL; Bao, GC; Yan, LJ

Le, Y; Yan, LJ (corresponding author), Guizhou Univ, Sch Pharmaceut Sci, Guiyang 550025, Peoples R China.; Li, YL (corresponding author), Guangdong Univ Technol, Fac Light Ind & Chem Engn, Guangzhou 510006, Peoples R China.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2021; 36 (1): 1205

Abstract

In this paper, a set of 3-methylquniazolinone derivatives were designed, synthesised, and studied the preliminary structure-activity relationship for ......

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