Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms

Davis, FM; Tsoi, LC; Melvin, WJ; DenDekker, A; Wasikowski, R; Joshi, AD; Wolf, S; Obi, AT; Billi, AC; Xing, XY; Audu, C; Moore, BB; Kunkel, SL; Daugherty, A; Lu, HS; Gudjonsson, JE; Gallagher, KA

Davis, FM; Gallagher, KA (corresponding author), Univ Michigan, Dept Surg, Sect Vasc Surg, Ann Arbor, MI 48109 USA.; Davis, FM; Gallagher, KA (corresponding author), Univ Michigan, Dept Microbiol & Immunol, Ann Arbor, MI 48109 USA.

JOURNAL OF EXPERIMENTAL MEDICINE, 2021; 218 (6):

Abstract

Abdominal aortic aneurysms (AAAs) are a life-threatening disease for which there is a lack of effective therapy preventing aortic rupture. During AAA ......

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