Let-7a regulates expression of beta(1)-adrenoceptors and forms a negative feedback circuit with the beta(1)-drenoceptor signaling pathway in chronic ischemic heart failure-MedSci.cn

Let-7a regulates expression of beta(1)-adrenoceptors and forms a negative feedback circuit with the beta(1)-drenoceptor signaling pathway in chronic ischemic heart failure

Du, Y; Zhang, MY; Zhao, W; Shu, Y; Gao, M; Zhuang, YN; Yang, T; Mu, W; Li, TT; Li, X; Sun, F; Pan, ZW; Lu, YJ

Pan, ZW; Lu, YJ (reprint author), Harbin Med Univ, Coll Pharm, Dept Pharmacol,Minist Educ, State Prov Key Labs Biomed Pharmaceut China,Key L, Harbin 150081, Heilongjiang, Peoples R China.; Lu, YJ (reprint author), Heilongjiang Acad Med Sci, Northern Trans

ONCOTARGET, 2017; 8 (5): 8752

Abstract

Background: The aim of the present study was to investigate the role of microRNA (miRNA) let-7a in down-regulation of beta(1)-adrenoceptors (beta(1)-A......

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Let-7a regulates expression of beta(1)-adrenoceptors and forms a negative feedback circuit with the beta(1)-drenoceptor signaling pathway in chronic ischemic heart failure

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