Synthesis of (-)-Cotylenol, a 14-3-3 Molecular Glue Component

Ting, SP; Snelson, DW; Huffman, TR; Kuroo, A; Sato, R; Shenvi, RA

Shenvi, RA (通讯作者)，Scripps Res, Dept Chem, La Jolla, CA 92037 USA.;Shenvi, RA (通讯作者)，Scripps Res, Skaggs Grad Sch Chem & Biol Sci, La Jolla, CA 92037 USA.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023; 145 (37): 20634

Abstract

Small molecules that modulate the 14-3-3 protein-protein interaction (PPI) network represent valuable therapeutics and tool compounds. However, access......

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