AT7867 Inhibits Human Colorectal Cancer Cells via AKT-Dependent and AKT-Independent Mechanisms

Zhang, SH; Deng, ZM; Yao, C; Huang, P; Zhang, Y; Cao, SB; Li, XC

Li, XC (reprint author), Nanjing Med Univ, Affiliated Hosp 1, Dept Gen Surg, Nanjing, Jiangsu, Peoples R China.; Cao, SB (reprint author), Nanjing Univ Chinese Med, Affiliated Hosp, Dept Gen Surg, Nanjing, Jiangsu, Peoples R China.

PLOS ONE, 2017; 12 (1):

Abstract

AKT is often hyper-activated in human colorectal cancers (CRC). This current study evaluated the potential anti-CRC activity by AT7867, a novel AKT an......

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