OTUD4-mediated GSDME deubiquitination enhances radiosensitivity in nasopharyngeal carcinoma by inducing pyroptosis

Di, MP; Miao, JJ; Pan, QZ; Wu, ZL; Chen, BY; Wang, MR; Zhao, JJ; Huang, HG; Bai, JW; Wang, QJ; Tang, Y; Li, YQ; He, J; Xiang, T; Weng, DS; Wang, L; Xia, JC; Zhao, C

Wang, L; Xia, JC; Zhao, C (通讯作者)，Sun Yat Sen Univ, Collaborat Innovat Ctr Canc Med, State Key Lab Oncol South China, Canc Ctr, Guangzhou 510060, Peoples R China.;Wang, L; Zhao, C (通讯作者)，Sun Yat Sen Univ, Dept Nasopharyngeal Carcinoma, Guangdong Key Lab Nasopharyngeal Carcinoma Diag &, Canc Ctr, Guangzhou 510060, Peoples R China.;Xia, JC (通讯作者)，Sun Yat Sen Univ, Dept Biotherapy, Canc Ctr, Guangzhou 510060, Peoples R China.

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2022; 41 (1):

Abstract

Background Radioresistance is the primary cause of nasopharyngeal carcinoma (NPC) treatment failure. Previous studies have focused on the deficits in ......

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