A functional polymorphism in the paired basic amino acid-cleaving enzyme 4 gene confers osteoarthritis risk in a population of Eastern China

He, J; Yang, HY; Xu, ZH; Li, J; Chen, G; Jiang, LF; Wu, LD; Zhou, XD

He, J (corresponding author), Jiaxing Univ, Affiliated Hosp 2, Dept Orthoped Surg, Jiaxing 314000, Peoples R China.

GENETICS AND MOLECULAR BIOLOGY, 2020; 43 (1):

Abstract

Paired basic amino acid-cleaving enzyme 4 (PACE4), a proprotein convertase, is involved in the activation of aggrecanases (ADAMTS-4 and ADAMTS-5) in o......

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