SIRT1 suppresses colorectal cancer metastasis by transcriptional repression of miR-15b-5p

Sun, LN; Zhi, Z; Chen, LY; Zhou, Q; Li, XM; Gan, WJ; Chen, S; Yang, M; Liu, Y; Shen, T; Xu, Y; Li, JM

Li, JM (reprint author), Soochow Univ, Med Coll, Dept Pathol & Pathophysiol, Suzhou 215123, Peoples R China.; Xu, Y (reprint author), Nanjing Med Univ, Dept Pathophysiol, Nanjing 210029, Jiangsu, Peoples R China.

CANCER LETTERS, 2017; 409 ( ): 104

Abstract

The class III deacetylase sirtuin 1 (SIRT1), a member of the sirtuin family proteins, plays a key role in many types of cancers including colorectal c......

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