Intratumoral delivery of tavokinogene telseplasmid yields systemic immune responses in metastatic melanoma patients

Algazi, A; Bhatia, S; Agarwala, S; Molina, M; Lewis, K; Faries, M; Fong, L; Levine, LP; Franco, M; Oglesby, A; Ballesteros-Merino, C; Bifulco, CB; Fox, BA; Bannavong, D; Talia, R; Browning, E; Le, MH; Pierce, RH; Gargosky, S; Tsai, KK; Twitty, C; Daud, AI

ANNALS OF ONCOLOGY, 2020; 31 (4): 532

Abstract

Background: Interleukin 12 (IL-12) is a pivotal regulator of innate and adaptive immunity. We conducted a prospective open-label, phase II clinical tr......

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