Intratumoral FoxP3(+)Helios(+) Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer

Khaja, ASS; Toor, SM; El Salhat, H; Ali, BR; Elkord, E

Elkord, E (reprint author), Hamad Bin Khalifa Univ, Qatar Biomed Res Inst, Qatar Fdn, Canc Res Ctr,Coll Sci & Engn, Doha, Qatar.; Elkord, E (reprint author), United Arab Emirates Univ, Dept Med Microbiol & Immunol, Coll Med & Hlth Sci, Al Ain, U Arab Emir

FRONTIERS IN IMMUNOLOGY, 2017; 8 ( ):

Abstract

Regulatory T cells (Tregs) can be antitumorigenic or pro-tumorigenic in colorectal cancer (CRC) depending on the presence of different Treg subsets wi......

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