Spreading of TDP-43 pathology via pyramidal tract induces ALS-like phenotypes in TDP-43 transgenic mice

Ding, XB; Xiang, Z; Qin, C; Chen, YK; Tian, HY; Meng, L; Xia, DH; Liu, H; Song, J; Fu, J; Ma, MM; Wang, XJ

Wang, XJ (corresponding author), Zhengzhou Univ, Affiliated Hosp 1, Dept Neurol, Zhengzhou 450052, Henan, Peoples R China.; Ma, MM (corresponding author), Zhengzhou Univ, Henan Prov Peoples Hosp, Dept Neurol, Affiliated Peoples Hosp, Zhengzhou 450003, Henan, Peoples R China.

ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2021; 9 (1):

Abstract

Transactive response DNA-binding protein 43 kDa (TDP-43) has been identified as the major component of ubiquitinated inclusions found in patients with......

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