Increasing deletion sizes and the efficiency of CRISPR/Cas9-mediated mutagenesis by SunTag-mediated TREX1 recruitment

Capdeville, N; Schindele, P; Puchta, H

Puchta, H (通讯作者),Karlsruhe Inst Technol KIT, Joseph Gottlieb Kolreuter Inst Plant Sci, Dept Mol Biol, Fritz Haber Weg 4, D-76131 Karlsruhe, Germany.

PLANT JOURNAL, 2023; ():

Abstract

Previously, it has been shown that mutagenesis frequencies can be improved by directly fusing the human exonuclease TREX2 to Cas9, resulting in a stro......

Full Text Link