Co-expression of TNF receptors 1 and 2 on melanomas facilitates soluble TNF-induced resistance to MAPK pathway inhibitors

Sander, CA; Rush, EA; Shi, J; Arantes, LMRB; Tesi, RJ; Ross, MA; Calderon, MJ; Watkins, SC; Kirkwood, JM; Ferris, RL; Butterfield, LH; Vujanovic, L

Vujanovic, L (通讯作者),Univ Pittsburgh, UPMC Hillman Canc Ctr, L2 19 Hillman Canc Ctr, 5117 Ctr Ave, Pittsburgh, PA USA.

JOURNAL OF TRANSLATIONAL MEDICINE, 2022; 20 (1):

Abstract

Background The effectiveness of MAPK pathway inhibitors (MAPKi) used to treat patients with BRAF-mutant melanoma is limited by a range of resistance m......

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