HER2 signaling regulates HER2 localization and membrane retention

Jeong, J; Kim, W; Kim, LK; VanHouten, J; Wysolmerski, JJ

Wysolmerski, JJ (reprint author), Yale Univ, Sch Med, Dept Internal Med, Sect Endocrinol & Metab, New Haven, CT 06510 USA.

PLOS ONE, 2017; 12 (4):

Abstract

ErbB2/HER2/Neu is a receptor tyrosine kinase that is overexpressed in 25-30% of human breast cancers, usually associated with amplification of the ERB......

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