Toll-like Receptor-9 (TLR-9) Signaling Is Crucial for Inducing Protective Immunity following Immunization with Genetically Modified Live Attenuated Leishmania Parasites

Bhattacharya, P; Gannavaram, S; Ismail, N; Saxena, A; Dagur, PK; Akue, A; KuKuruga, M; Nakhasi, HL

Bhattacharya, P; Nakhasi, HL (通讯作者)，Ctr Biol Evaluat & Res Food & Drug Adm, Div Emerging & Transfus Transmitted Dis, Silver Spring, MD 20993 USA.

PATHOGENS, 2023; 12 (4):

Abstract

No human vaccine is available for visceral leishmaniasis (VL). Live attenuated centrin gene-deleted L. donovani (LdCen(-/-)) parasite vaccine has been......

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