Simultaneous Determination of Rosuvastatin, Rosuvastatin-5S-lactone, and N-desmethyl Rosuvastatin in Human Plasma by UPLC-MS/MS and Its Application to Clinical Study

Bai, X; Wang, XP; He, GD; Zhang, B; Huang, M; Li, JL; Zhong, SL

Zhong, SL (reprint author), Guangdong Acad Med Sci, Guangdong Gen Hosp, Guangdong Cardiovasc Inst, 106 Zhongshan Rd,Weilun Bldg 1112, Guangzhou 510080, Guangdong, Peoples R China.; Li, JL (reprint author), Sun Yat Sen Univ, Sch Pharmaceut Sci, 132 Waihuan

DRUG RESEARCH, 2018; 68 (6): 328

Abstract

Objective A rapid and sensitive ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) assay was developed and validated for th......

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