Optimization of a medium composition for the heterologous production of Alcaligenes faecalis penicillin G acylase in Bacillus megaterium

Lopes, W; Deolindo, P; Costa, AAD; da Silva, MTG; de Miranda, OP; Pacheco, GJ

Pacheco, GJ (通讯作者),Fundacao Oswaldo Cruz, Inst Drug Technol, Rio De Janeiro, RJ, Brazil.

PROTEIN EXPRESSION AND PURIFICATION, 2023; 210 ():

Abstract

Penicillin G acylase (PGA) is a strategic enzyme in the production processes of beta-lactam antibiotics. High demand for & beta;-lactam semisynthe......

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