Targeted Therapy to beta 3 Integrin Reduces Chemoresistance in Breast Cancer Bone Metastases

Fox, GC; Su, XM; Davis, JL; Xu, YL; Kwakwa, KA; Ross, MH; Fontana, F; Xiang, JY; Esser, AK; Cordell, E; Pagliai, K; Dang, H; Sivapackiam, J; Stewart, SA; Maher, CA; Bakewell, SJ; Fitzpatrick, JAJ; Sharma, V; Achilefu, S; Veis, DJ; Lanza, GM; Weilbaecher, KN

Weilbaecher, KN (corresponding author), Washington Univ, Sch Med, Campus Box 8069,660 South Euclid Ave, St Louis, MO 63110 USA.

MOLECULAR CANCER THERAPEUTICS, 2021; 20 (6): 1183

Abstract

Breast cancer bone metastases are common and incurable. Tumoral integrin beta 3 (beta 3) expression is induced through interaction with the bone micro......

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