Conformational Sampling Deciphers the Chameleonic Properties of a VHL-Based Degrader

Ermondi, G; Jimenez, DG; Sebastiano, MR; Kihlberg, J; Caron, G

Caron, G (通讯作者),Univ Torino, Dept Mol Biotechnol & Hlth Sci, Quarello 15, I-10135 Turin, Italy.

PHARMACEUTICS, 2023; 15 (1):

Abstract

Chameleonicity (the capacity of a molecule to adapt its conformations to the environment) may help to identify orally bioavailable drugs in the beyond......

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