A humanized CD3 epsilon-knock-in mouse model for pre-clinical testing of anti-human CD3 therapy

Crespo, J; Koh, YT; Hu, NJ; Moore, PA; Bonvini, E; Glasebrook, AL; Martin, AP; Benschop, RJ

Benschop, RJ (corresponding author), Eli Lilly & Co, Lilly Res Labs, Immunol Res, Indianapolis, IN 46285 USA.

PLOS ONE, 2021; 16 (2):

Abstract

Pre-clinical murine models are critical for translating drug candidates from the bench to the bedside. There is interest in better understanding how a......

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