Hepatocyte-specific HIF-1 alpha ablation improves obesity-induced glucose intolerance by reducing first-pass GLP-1 degradation

Lee, YS; Riopel, M; Cabrales, P; Bandyopadhyay, GK

Lee, YS (reprint author), Univ Calif San Diego, Dept Med, Div Endocrinol & Metab, La Jolla, CA 92093 USA.

SCIENCE ADVANCES, 2019; 5 (7):

Abstract

The decrease in incretin effects is an important etiologic component of type 2 diabetes with unknown mechanisms. In an attempt to understand obesity-i......

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