IRF-7 Mediates Type I IFN Responses in Endotoxin-Challenged Mice

Sin, WX; Yeong, JPS; Lim, TJF; Su, IH; Connolly, JE; Chin, KC

Chin, KC (corresponding author), Agcy Sci Technol & Res, Inst Mol & Cell Biol, Singapore, Singapore.; Chin, KC (corresponding author), Natl Univ Singapore, Dept Physiol, NUS Yong Loo Lin Sch Med, Singapore, Singapore.

FRONTIERS IN IMMUNOLOGY, 2020; 11 ():

Abstract

IRF-7 mediates robust production of type I IFN via MyD88 of the TLR9 pathway in plasmacytoid dendritic cells (pDCs). Previous in vitro studies using b......

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