Chaperone-mediated autophagy degradation of IGF-1R beta induced by NVP-AUY922 in pancreatic cancer

Xue, NN; Lai, FF; Du, TT; Ji, M; Liu, D; Yan, CH; Zhang, S; Yu, XM; Jin, J; Chen, XG

Jin, J; Chen, XG (reprint author), Chinese Acad Med Sci, State Key Lab Bioact Subst & Funct Nat Med, Beijing Key Lab Nonclin Drug Metab & PK PD Study, Inst Mat Med,Peking Union Med Coll, Beijing 100050, Peoples R China.

CELLULAR AND MOLECULAR LIFE SCIENCES, 2019; 76 (17): 3433

Abstract

Enhancement of insulin-like growth factor 1 receptor (IGF-IR) degradation by heat shock protein 90 (HSP90) inhibitor is a potential antitumor therapeu......

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