Design and Synthesis Studies of α-Methylene-γ-butyrolactones Antagonists of GPR52

Shen, DH; Li, X; Guo, SM; Xie, X; Nan, FJ

Xie, X; Nan, FJ (通讯作者)，Univ Chinese Acad Sci, Beijing 100049, Peoples R China.;Xie, X; Nan, FJ (通讯作者)，Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China.;Xie, X; Nan, FJ (通讯作者)，Hangzhou Inst Adv Study, Hangzhou 310024, Peoples R China.

CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023; 43 (11): 3916

Abstract

GPR52 is an orphan G protein-coupled receptor, which is highly expressed in the striatum and associated with Huntingdon's disease (HD), a neurodegener......

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