Systematic analysis and molecular profiling of EGFR allosteric inhibitor cross-reactivity across the proto-oncogenic ErbB family kinases by integrating dynamics simulation, energetics calculation and biochemical assay

Ma, YL; Qi, BL; Ning, MY; Zhang, LJ; An, ZY; Zhao, J

Zhao, J (通讯作者)，Hebei Med Univ, Cangzhou Cent Hosp, Dept Pharm, Cangzhou 061000, Peoples R China.

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2022; 51 (3): 283

Abstract

Human ErbB family of proteins contains four receptor tyrosine kinases (EGFR, Her2, Her3 and Her4) and has been established as a group of attractive dr......

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