NRG1 fusions in breast cancer

Howarth, KD; Mirza, T; Cooke, SL; Chin, SF; Pole, JC; Turro, E; Eldridge, MD; Garcia, RM; Rueda, OM; Boursnell, C; Abraham, JE; Caldas, C; Edwards, PAW

Howarth, KD; Edwards, PAW (corresponding author), Univ Cambridge, Hutchison MRC Res Ctr, Cambridge CB2 0XZ, England.; Howarth, KD; Edwards, PAW (corresponding author), Univ Cambridge, Dept Pathol, Cambridge, England.; Howarth, KD (corresponding author), Inivata Ltd, Babraham Res Pk, Cambridge CB22 3FH, England.; Edwards, PAW (corresponding author), Univ Cambridge, Dept Oncol, Li Ka Shing Ctr, Canc Res UK Cambridge Inst, Cambridge CB2 0RE, England.; Edwards, PAW (corresponding author), Univ Cambr

BREAST CANCER RESEARCH, 2021; 23 (1):

Abstract

BackgroundNRG1 gene fusions may be clinically actionable, since cancers carrying the fusion transcripts can be sensitive to tyrosine kinase inhibitors......

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